CAS RN 935666-88-9

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Potent and selective JAK2 inhibitor; antiangiogenic

MedChemExpress AZD-1480 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50s of 1.3 nM and <0.4 nM, respectively.

Molekylformel	C₁₄H₁₄ClFN₈
Rekommenderad förvaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt	348.77
Hållbarhet	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation	DMSO : 50 mg/mL (143.36 mM; Need ultrasonic)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	White
CAS	935666-88-9
LEDER	ClC1=C(N=C(N=C1)N[C@@H](C)C2=NC=C(C=N2)F)NC3=NNC(C)=C3
Molekylvikt (g/mol)	348.77
Kemiskt namn eller material	AZD-1480
Procent renhet	98.02%
För användning med (applikation)	Cancer-Kinase/protease

Potent and selective JAK2 inhibitor; antiangiogenic