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CFLAR/FLIP Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10394-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionFLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
|c FLIP, c FLIPL, c FLIPR, c FLIPS, CASH, CASP8AP1, Caspase eight related protein, Caspase homolog, Casper, CFLAR, CLARP, FLAME, FLAME 1, FLAME1, FLIP, I FLICE, Inhibitor of FLICE, MRIT, Usurpin|
|Antigen Affinity Chromatography|
|Immunofluorescence, Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|CFLAR/FLIP Fusion Protein Ag0593|