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CFLAR/FLIP Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10394-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16886753

  • 1656.73 SEK / 20µL
Estimated Shipment: 02-04-2024
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Description

Description

FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Specifications

Specifications

CFLAR/FLIP
Polyclonal
Unconjugated
CFLAR
c FLIP, c FLIPL, c FLIPR, c FLIPS, CASH, CASP8AP1, Caspase eight related protein, Caspase homolog, Casper, CFLAR, CLARP, FLAME, FLAME 1, FLAME1, FLIP, I FLICE, Inhibitor of FLICE, MRIT, Usurpin
Rabbit
Antigen Affinity Chromatography
RUO
8837
-20°C
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunofluorescence
0.72 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O15519
CFLAR
CFLAR/FLIP Fusion Protein Ag0593
20 μL
Primary
Human
Antibody
IgG
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