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CHOP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 15204-1-AP-150UL
Additional Details : Weight : 0.00010kg
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DescriptionGADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
|CEBPZ, CHOP, CHOP 10, DDIT 3, DDIT3, GADD153|
|Antigen Affinity Chromatography|
|13198, 1649, 29467|
|Western Blot, Immunohistochemistry (Paraffin), Flow Cytometry|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P35638, P35639, Q62857|
|CHOP Fusion Protein Ag7354|
|Rat, Mouse, Human|