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HTR1B Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 22189-1-AP-150UL
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Description
Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. In situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei.Specifications
| HTR1B | |
| Polyclonal | |
| Unconjugated | |
| HTR1B | |
| 5 HT 1B, 5 HT 1D beta, 5 HT1B, 5 HT1DB, HTR1B, HTR1D2, HTR1DB, S12, Serotonin 1D beta receptor, Serotonin receptor 1B | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3351 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.51 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P28222 | |
| HTR1B | |
| HTR1B Fusion Protein Ag16753 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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Product Title
HTR1B Rabbit anti-Human, Polyclonal, Proteintech > 150 μL; Unconjugated
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