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Nukleosid och nukleotidanaloger

Nukleosider och nukleotider som innehåller en nukleinsyraanalog (en förening som strukturellt liknar naturligt förekommande RNA eller DNA); analoga nukleobaser har typiskt bland annat olika basparnings- och basstaplingsegenskaper.
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1 – 4 av 4 Resultat
2

ent-Emtricitabine, TRC

CAS: 137530-41-7 Kemiskt namn eller material: ent-Emtricitabine Formel vikt: 247.0427 InChI formel: InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m1/s1 IUPAC-namn: 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one Molekylformel: C8 H10 F N3 O3 S Molekylvikt (g/mol): 247.25 Rekommenderad förvaring: 4°C LEDER: NC1=NC(=O)N(C=C1F)[C@H]2CS[C@@H](CO)O2 Synonym: 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)-,1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(+)-2'-Deoxy-3'-thia-5-fluorocytidine,(+)-FTC,(2'S,5'R)-Emtricitabine,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

Rekommenderad förvaring 4°C
Molekylformel C8 H10 F N3 O3 S
InChI formel InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m1/s1
IUPAC-namn 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Formel vikt 247.0427
CAS 137530-41-7
LEDER NC1=NC(=O)N(C=C1F)[C@H]2CS[C@@H](CO)O2
Molekylvikt (g/mol) 247.25
Synonym 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)-,1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(+)-2'-Deoxy-3'-thia-5-fluorocytidine,(+)-FTC,(2'S,5'R)-Emtricitabine,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
Kemiskt namn eller material ent-Emtricitabine
3

cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione, TRC

CAS: 145986-11-4 Kemiskt namn eller material: cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione InChI formel: InChI=1S/C8H9FN2O4S/c9-4-1-11(8(14)10-7(4)13)5-3-16-6(2-12)15-5/h1,5-6,12H,2-3H2,(H,10,13,14)/t5-,6+/m0/s1 Molekylformel: C8H9FN2O4S Molekylvikt (g/mol): 248.23 Rekommenderad förvaring: -20°C LEDER: O=C1C(F)=CN([C@@H]2CS[C@H](CO)O2)C(N1)=O Synonym: (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione

Rekommenderad förvaring -20°C
Molekylformel C8H9FN2O4S
InChI formel InChI=1S/C8H9FN2O4S/c9-4-1-11(8(14)10-7(4)13)5-3-16-6(2-12)15-5/h1,5-6,12H,2-3H2,(H,10,13,14)/t5-,6+/m0/s1
CAS 145986-11-4
LEDER O=C1C(F)=CN([C@@H]2CS[C@H](CO)O2)C(N1)=O
Molekylvikt (g/mol) 248.23
Synonym (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione
Kemiskt namn eller material cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
4

4’-Epi Lamivudine, TRC

CAS: 139757-68-9 Kemiskt namn eller material: Trans-Lamivudine Formel vikt: 229.0521 InChI formel: InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m1/s1 IUPAC-namn: 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one Molekylformel: C8 H11 N3 O3 S Molekylvikt (g/mol): 229.26 Rekommenderad förvaring: -20°C LEDER: NC1=NC(=O)N(C=C1)[C@H]2CS[C@H](CO)O2 Synonym: 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-trans)- (9CI),1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,trans(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane,4'-Epi Lamivudine,4'-epi-Lamivudine,4'-Epilamivudine,trans-Lamivudine,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one,(2'R-trans)-Lamivudine

Rekommenderad förvaring -20°C
Molekylformel C8 H11 N3 O3 S
InChI formel InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m1/s1
IUPAC-namn 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Formel vikt 229.0521
CAS 139757-68-9
LEDER NC1=NC(=O)N(C=C1)[C@H]2CS[C@H](CO)O2
Molekylvikt (g/mol) 229.26
Synonym 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-trans)- (9CI),1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,trans(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane,4'-Epi Lamivudine,4'-epi-Lamivudine,4'-Epilamivudine,trans-Lamivudine,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one,(2'R-trans)-Lamivudine
Kemiskt namn eller material Trans-Lamivudine