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Nukleosid och nukleotidanaloger

Nukleosider och nukleotider som innehåller en nukleinsyraanalog (en förening som strukturellt liknar naturligt förekommande RNA eller DNA); analoga nukleobaser har typiskt bland annat olika basparnings- och basstaplingsegenskaper.
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1 – 5 av 5 Resultat
2

ent-Emtricitabine, TRC

CAS: 137530-41-7 Molekylformel: C8 H10 F N3 O3 S Molekylvikt (g/mol): 247.25 Synonym: 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)-,1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(+)-2'-Deoxy-3'-thia-5-fluorocytidine,(+)-FTC,(2'S,5'R)-Emtricitabine,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one IUPAC-namn: 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one LEDER: NC1=NC(=O)N(C=C1F)[C@H]2CS[C@@H](CO)O2

Molekylformel C8 H10 F N3 O3 S
IUPAC-namn 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
CAS 137530-41-7
LEDER NC1=NC(=O)N(C=C1F)[C@H]2CS[C@@H](CO)O2
Molekylvikt (g/mol) 247.25
Synonym 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)-,1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(+)-2'-Deoxy-3'-thia-5-fluorocytidine,(+)-FTC,(2'S,5'R)-Emtricitabine,4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
3

cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione, TRC

CAS: 145986-11-4 Molekylformel: C8H9FN2O4S Molekylvikt (g/mol): 248.23 Synonym: (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione LEDER: O=C1C(F)=CN([C@@H]2CS[C@H](CO)O2)C(N1)=O

Molekylformel C8H9FN2O4S
CAS 145986-11-4
LEDER O=C1C(F)=CN([C@@H]2CS[C@H](CO)O2)C(N1)=O
Molekylvikt (g/mol) 248.23
Synonym (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione
4

ent-Lamivudine, TRC

CAS: 134680-32-3 Molekylformel: C8H11N3O3S Molekylvikt (g/mol): 229.26 Synonym: 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(2S-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(+)-BCH 189,2',3'-Dideoxy-3'-thiacytidine,2'-Deoxy-3'-thiacytidine,3TC,NSC 620753,cis(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane,Lamivudine EP Impurity D LEDER: C1[C@@H](O[C@@H](S1)CO)N2C=CC(=NC2=O)N

Molekylformel C8H11N3O3S
CAS 134680-32-3
LEDER C1[C@@H](O[C@@H](S1)CO)N2C=CC(=NC2=O)N
Molekylvikt (g/mol) 229.26
Synonym 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(2S-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,(+)-BCH 189,2',3'-Dideoxy-3'-thiacytidine,2'-Deoxy-3'-thiacytidine,3TC,NSC 620753,cis(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane,Lamivudine EP Impurity D
5

4’-Epi Lamivudine, TRC

CAS: 139757-68-9 Molekylformel: C8 H11 N3 O3 S Molekylvikt (g/mol): 229.26 Synonym: 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-trans)- (9CI),1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,trans(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane,4'-Epi Lamivudine,4'-epi-Lamivudine,4'-Epilamivudine,trans-Lamivudine,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one,(2'R-trans)-Lamivudine IUPAC-namn: 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one LEDER: NC1=NC(=O)N(C=C1)[C@H]2CS[C@H](CO)O2

Molekylformel C8 H11 N3 O3 S
IUPAC-namn 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
CAS 139757-68-9
LEDER NC1=NC(=O)N(C=C1)[C@H]2CS[C@H](CO)O2
Molekylvikt (g/mol) 229.26
Synonym 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-trans)- (9CI),1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone,trans(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane,4'-Epi Lamivudine,4'-epi-Lamivudine,4'-Epilamivudine,trans-Lamivudine,4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one,(2'R-trans)-Lamivudine