missing translation for 'onlineSavingsMsg'
Learn More
Learn More
UPF3B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 23301-1-AP-20UL
This item is not returnable.
View return policy
Description
UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.Specifications
UPF3B | |
Polyclonal | |
Unconjugated | |
UPF3B | |
HUPF3B, hUpf3p X, MRXS14, RENT3B, UPF3B, UPF3X | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
313449, 65109, 68134 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.61 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q9BZI7 | |
Upf3b | |
UPF3B Fusion Protein Ag18568 | |
20 μL | |
Primary | |
Mouse, Rat, Human | |
Antibody | |
IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
UPF3B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 20 μL; Unconjugated
Spot an opportunity for improvement?Share a Content Correction