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Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Pan Caspase Inhibitor Z-VAD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.
Competitive serine protease inhibitor
Non-selective P2 agonist; analog of ATP (Cat. No. 3245)
Potent calcineurin inhibitor; immunosuppressant
Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination
Potent and selective PERK inhibitor; orally bioavailable
Reagent used in the measurement of cell proliferation
Potent PTEN inhibitor
Inverse agonist of the constitutive androstane receptor (CAR)
Selective negative allosteric modulator of mGlu3
S1P2 receptor antagonist
Potent and selective Lck and Src inhibitor; also inhibits SIK
Cell permeable compound; hydrolyzed to become fluorescent in living cells
Selective and ATP-competitive Kif18A inhibitor
ATP-competitive inhibitor of p97 ATPase