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Phenylacetic acids

Organic compounds that consist of a phenyl group with a carboxylic acid group substitution; a carboxylic acid contains a carbon atom bonded to both a carbonyl group and a hydroxyl group.
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1 – 14 av 14 Resultat
1

Homogentisic Acid, TRC

CAS: 451-13-8 Molekylformel: C8 H8 O4 Molekylvikt (g/mol): 168.15 Synonym: 2,5-Dihydroxybenzeneacetic Acid,2,5-Dihydroxy-α-toluic Acid,2,5-Dihydroxyphenylacetic Acid,Alcapton,Homogentisinic Acid,NSC 88940 IUPAC-namn: 2-(2,5-dihydroxyphenyl)acetic acid LEDER: OC(=O)Cc1cc(O)ccc1O

Molekylformel C8 H8 O4
IUPAC-namn 2-(2,5-dihydroxyphenyl)acetic acid
CAS 451-13-8
LEDER OC(=O)Cc1cc(O)ccc1O
Molekylvikt (g/mol) 168.15
Synonym 2,5-Dihydroxybenzeneacetic Acid,2,5-Dihydroxy-α-toluic Acid,2,5-Dihydroxyphenylacetic Acid,Alcapton,Homogentisinic Acid,NSC 88940
2

Felbinac, MedChemExpress

MedChemExpress Felbinac is a potent non-steroidal anti-inflammatory agent, used to treat muscle inflammation and arthritis.

ENCOMPASS_PREFERRED
3

GW3965 hydrochloride, MedChemExpress

MedChemExpress GW3965 hydrochloride is a potent and selective liver X receptor (LXR) agonist with EC50s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively.

ENCOMPASS_PREFERRED
Molekylformel C33H32Cl2F3NO3
Rekommenderad förvaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt 618.51
Hållbarhet 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Hälsofara 1 H302∣H318∣H413
Löslighetsinformation DMSO : 100 mg/mL (161.68 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 405911-17-3
LEDER ClC1=C(C(F)(F)F)C=CC=C1CN(CC(C2=CC=CC=C2)C3=CC=CC=C3)CCCOC4=CC(CC(O)=O)=CC=C4.[H]Cl
Molekylvikt (g/mol) 618.51
Kemiskt namn eller material GW3965 hydrochloride
Procent renhet 98.13%
För användning med (applikation) COVID-19-immunoregulation
4

ONO-7300243, MedChemExpress

MedChemExpress ONO-7300243 is a novel, potent lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 μM.

ENCOMPASS_PREFERRED
Molekylformel C28H31NO5
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 461.55
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Hälsofara 1 H302∣H315∣H319∣H335
Löslighetsinformation DMSO : 100 mg/mL (216.66 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 638132-34-0
LEDER O=C(O)CC1=CC=C(CN(C(C2=CC(OC)=C(C)C(OC)=C2)=O)CCCC3=CC=CC=C3)C=C1
Molekylvikt (g/mol) 461.55
Kemiskt namn eller material ONO-7300243
Procent renhet 98.14%
För användning med (applikation) COVID-19-immunoregulation
5

TES-1025, MedChemExpress

MedChemExpress TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13 nM.

ENCOMPASS_PREFERRED
Molekylformel C18H13N3O3S2
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 383.44
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation DMSO : 100 mg/mL (260.80 mM; Need warming)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Yellow
CAS 1883602-21-8
LEDER O=C1C(C#N)=C(C2=CC=CS2)N=C(SCC3=CC=CC(CC(O)=O)=C3)N1
Molekylvikt (g/mol) 383.44
Kemiskt namn eller material TES-1025
Procent renhet 95.11%
För användning med (applikation) Metabolism-protein/nucleotide metabolism
6

Evocalcet, MedChemExpress

MedChemExpress Evocalcet has an activating effect on calcium sensing receptor (CaSR) extracted from patent WO 2017061621 A1, compound A.

ENCOMPASS_PREFERRED
Molekylformel C24H26N2O2
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 374.48
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation DMSO : 30 mg/mL (80.11 mM; Need ultrasonic and warming)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Off-White
CAS 870964-67-3
LEDER O=C(O)CC1=CC=C(N2C[C@@H](N[C@@H](C3=C4C=CC=CC4=CC=C3)C)CC2)C=C1
Molekylvikt (g/mol) 374.48
Synonym KHK7580
Kemiskt namn eller material Evocalcet
Procent renhet 99.05%
För användning med (applikation) Metabolism-protein/nucleotide metabolism
7

AM211, MedChemExpress

MedChemExpress AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.

ENCOMPASS_PREFERRED
Molekylformel C27H27F3N2O4
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 500.51
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation DMSO : ≥ 125 mg/mL (249.75 mM)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 1175526-27-8
LEDER O=C(O)CC1=CC(C2=CC=C(C(F)(F)F)C=C2CN(CC)C(NCC3=CC=CC=C3)=O)=C(OC)C=C1
Molekylvikt (g/mol) 500.51
Synonym AM211 free acid
Kemiskt namn eller material AM211
Procent renhet 98.11%
För användning med (applikation) COVID-19-immunoregulation
8

AM966, MedChemExpress

MedChemExpress AM966 is a high affinity, selective, oral LPA1-antagonist, inhibits LPA-stimulated intracellular calcium release (IC50=17 nM).

ENCOMPASS_PREFERRED
Molekylformel C27H23ClN2O5
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 490.93
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Hälsofara 1 H302∣H315∣H319∣H335
Löslighetsinformation DMSO : 100 mg/mL (203.70 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Off-White
CAS 1228690-19-4
LEDER O=C(O)CC1=CC=C(C2=CC=C(C3=C(NC(O[C@@H](C4=CC=CC=C4Cl)C)=O)C(C)=NO3)C=C2)C=C1
Molekylvikt (g/mol) 490.93
Kemiskt namn eller material AM966
Procent renhet 98.64%
För användning med (applikation) COVID-19-immunoregulation
9

AM095 free acid, MedChemExpress

MedChemExpress AM095 (free acid) is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.

ENCOMPASS_PREFERRED
Molekylformel C27H24N2O5
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 456.49
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Löslighetsinformation DMSO : 67.3 mg/mL (147.43 mM; Need ultrasonic and warming)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Off-White
CAS 1228690-36-5
LEDER O=C(O)CC1=CC=C(C2=CC=C(C3=C(NC(O[C@@H](C4=CC=CC=C4)C)=O)C(C)=NO3)C=C2)C=C1
Molekylvikt (g/mol) 456.49
Kemiskt namn eller material AM095 free acid
Procent renhet 98.07%
För användning med (applikation) COVID-19-immunoregulation
10

Diclofenac, MedChemExpress

MedChemExpress Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

ENCOMPASS_PREFERRED
Molekylformel C14H11Cl2NO2
Rekommenderad förvaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formel vikt 296.15
Hållbarhet Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Hälsofara 1 H302∣H315∣H319∣H335
Löslighetsinformation DMSO : ≥ 3.5 mg/mL (11.82 mM)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Off-White
CAS 15307-86-5
LEDER O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl
Molekylvikt (g/mol) 296.15
Kemiskt namn eller material Diclofenac
Procent renhet 99.91%
För användning med (applikation) COVID-19-immunoregulation
11

Olopatadine hydrochloride, MedChemExpress

MedChemExpress Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis.

ENCOMPASS_PREFERRED
Molekylformel C21H24ClNO3
Rekommenderad förvaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt 373.87
Hållbarhet 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Hälsofara 1 H301∣H400
Löslighetsinformation DMSO : 50 mg/mL (133.74 mM; Need ultrasonic) ∣H2O : 6.67 mg/mL (17.84 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 140462-76-6
LEDER O=C(O)CC1=CC=C(C/2=C1)OCC3=CC=CC=C3C2=C\CCN(C)C.Cl
Molekylvikt (g/mol) 373.87
Synonym ALO4943A KW4679
Kemiskt namn eller material Olopatadine hydrochloride
Procent renhet 99.97%
För användning med (applikation) COVID-19-immunoregulation
12

RGX-104 hydrochloride, MedChemExpress

MedChemExpress RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene.

ENCOMPASS_PREFERRED
Molekylformel C34H34Cl2F3NO3
Rekommenderad förvaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt 632.54
Hållbarhet 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Löslighetsinformation DMSO : 150 mg/mL (237.14 mM; ultrasonic and warming and heat to 60°C)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 610318-03-1
LEDER O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4)C)=C1.Cl
Molekylvikt (g/mol) 632.54
Kemiskt namn eller material RGX-104 hydrochloride
Procent renhet 99.14%
För användning med (applikation) COVID-19-immunoregulation
13

RGX-104, MedChemExpress

MedChemExpress RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene.

ENCOMPASS_PREFERRED
Molekylformel C34H33ClF3NO3
Rekommenderad förvaring 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Formel vikt 596.08
Hållbarhet 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Hälsofara 1 H302∣H315∣H319∣H335
Löslighetsinformation DMSO : 100 mg/mL (167.76 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 610318-54-2
LEDER O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4)C)=C1
Molekylvikt (g/mol) 596.08
Kemiskt namn eller material RGX-104
Procent renhet 99.35%
För användning med (applikation) Cancer-programmed cell death
14

Diclofenac diethylamine, MedChemExpress

MedChemExpress Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

ENCOMPASS_PREFERRED
Molekylformel C18H22Cl2N2O2
Rekommenderad förvaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt 369.29
Hållbarhet 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Löslighetsinformation DMSO : 150 mg/mL (406.18 mM; Need ultrasonic)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg Off-White
CAS 78213-16-8
LEDER O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl.CCNCC
Molekylvikt (g/mol) 369.29
Kemiskt namn eller material Diclofenac diethylamine
Procent renhet 99.55%
För användning med (applikation) COVID-19-immunoregulation