General Cell Based Assays

General Cell Based Assays
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Thermo Scientific™ Tango™ HRH3-bla U2OS DA Assay Kit
The Tango™ HRH3-bla U2OS DA (Division Arrested) cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ Kinase Tracer 236, 50 μM
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1 Cell Line
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
GeneBLAzer™ GeneBLAzer™ GCGR-CRE-bla CHO-K1 Cells
GeneBLAzer™ GCGR-CRE-bla CHO-K1 Cells contain the human glucagon receptor (GCGR).
GeneBLAzer™ GeneBLAzer™ GIPR-CRE-bla HEK 293T Cells
GeneBLAzer™ GIPR-CRE-bla HEK 293T Cells contain the human Gastric Inhibitory Peptide Receptor (GIPR).
Thermo Scientific™ CellSensor™ T-REx™ FOXO3 DBE-bla HeLa Cell Line
The CellSensor™ T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression, along with a tetracycline repressor and tetracycline (or the tetracycline analog doxycycline)-inducible FOXO3 constructs.
Thermo Scientific™ CellSensor™ CRE-bla HEK 293T Cell Line
The CellSensor™ CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE).
Thermo Scientific™ CellSensor™ NFkB-bla ME-180 Cell Line
The CellSensor™ NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells.
Thermo Scientific™ Tango™ CXCR4-bla U2OS Cells
The Tango™ CXCR4-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 4 (CXCR4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ OPRL1-bla U2OS Cells
The Tango™ OPRL1-bla U2OS cells contain the human Opioid Receptor-Like 1 (OPRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ T-Rex™ GPR119-CRE-bla CHO-K1 Cells
The GeneBLAzer™ T-Rex™ GPR119-CRE-bla CHO-K1 cells contain the human G-Protein Receptor 119 (GPR119), stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Invitrogen™ BacMam LRRK2-GFP Wild Type Reagent
BacMam LRRK2-GFP Wild Type Reagent is a modified insect cell virus (baculovirus) that enables easy, efficient, and titratable overexpression of full-length wild type LRRK2-GFP in your choice of cellular background, including primary neurons and neuroblastoma cell lines.
Thermo Scientific™ GeneBLAzer™ ADORA3-Gα15-NFAT-bla CHO-K1 cells
GeneBLAzer™ ADORA3-Ga15-NFAT-bla CHO-K1 cells contain the human Adenosine A3 Receptor (ADORA3) stably integrated into the GeneBLAzer™ Ga15-NFAT-bla CHO-K1 cell line.
GeneBLAzer™ GeneBLAzer™ GnRHR-NFAT-bla CHO-K1 Cells
GeneBLAzer™ GnRHR-NFAT-bla CHO-K1 Cells contain the human gonadotropin-releasing hormone receptor.