General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ Tango™ HRH3-bla U2OS DA Assay Kit
The Tango™ HRH3-bla U2OS DA (Division Arrested) cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ Kinase Tracer 236, 50 μM
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1 Cell Line
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
GeneBLAzer™ GeneBLAzer™ GCGR-CRE-bla CHO-K1 Cells
GeneBLAzer™ GCGR-CRE-bla CHO-K1 Cells contain the human glucagon receptor (GCGR).
Thermo Scientific™ GeneBLAzer™ PAC1-CRE-bla CHO-K1 Cells
The GeneBLAzer™ PAC1-CRE-bla CHO-K1 cells contain the human Adenylate Cyclase Activating Polypeptide 1 Receptor 1 (ADCYAP1R/PAC1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ EDG7-NFAT-bla HEK 293T Cells
GeneBLAzer™ EDG7-NFAT-bla HEK293T cells contain the human Endothelial Differentiation Gene (EDG7) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Thermo Scientific™ CellSensor™ irf1-bla HEL Cell Line
Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines.
Thermo Scientific™ GeneBLAzer™ ADRB1-CRE-bla CHO-K1 Cells
The GeneBLAzer ™ ADRB1-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-1 Receptor (ADRB1), (Accession No. NM_000684) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ LanthaScreen™ IkB alpha GripTite™ Cell Line
The LanthaScreen™ IkB alpha GripTite™ cell line contains a fusion protein consisting of the cDNA encoding for GFP and IkB (GFP is fused to the N-terminus of IkB alpha) under the control of a CMV promoter stably transfected into GripTite™ cells.
Thermo Scientific™ GeneBLAzer™ H2-CRE-bla HEK 293T Cells
GeneBLAzer™ H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor™ CRE-bla HEK293T cell line.
Thermo Scientific™ CellSensor™ irf1-bla TF-1 Cell Line
Jak/Stat signaling pathways play essential roles in cellular responses to distinct cytokines. One of the Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response to Interleukin-3 (IL-3), prolactin, erythropoietin (Epo), and granulocyte-macrophage colony stimulating factor (GM-CSF).
Thermo Scientific™ CellSensor™ T-REx™ FOXO3 DBE-bla HeLa Cell Line
The CellSensor™ T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression, along with a tetracycline repressor and tetracycline (or the tetracycline analog doxycycline)-inducible FOXO3 constructs.
Thermo Scientific™ GeneBLAzer™ PR DA Assay Kit
GeneBLAzer™PR DA (Division Arrested) cells and PR-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Progesterone Receptor (PR) fused to the DNAbinding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ P2RY6 CHO-K1 DA Assay Kit
GeneBLAzer™ P2RY6 CHO-K1 DA (Division Arrested) cells and P2RY6-NFAT-bla CHO-K1 cells contain the human purinergic receptor P2, G protein-coupled, 6 (P2RY6) receptor stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.